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When to Consider Second-line Therapies

  • 4 days ago
  • 1 min read

Effective medical treatment is crucial for maintaining quality of life and optimal function. Exercise and oral medications often provide excellent symptom control for many years. When these symptoms start to become inconsistent, second-line therapies can help re-establish control.


Some people consider second-line therapies as a “last resort” option, or believe their symptoms need to be severe before they consider this. While they can work very well in this instance, evidence suggests that earlier intervention is preferable as it allows people living with PD to maintain a better quality of life for longer.  


When should people consider second-line therapies according to the “5-2-1” guide?

This guide was established by an expert panel of Neurologists and states that if an individual with PD is experiencing 1 or more of the following, they should consider second-line therapies:

·      Taking 5 or more doses of levodopa per day

·      Experiencing 2 or more hours of “off” time per day

·      Having 1 or more hours of troublesome dyskinesia per day


If any of these are occurring, second-line therapy options may be a worthwhile consideration.


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Medical device image, stethoscope and medication

 
 
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